Kansas City leans on Hollywood Brown as the Week 1 focal point in Brazil with Rasheed Rice out six weeks, while Xavier Worthy and Tyquan Thornton pace the speed elements. Kelce and JuJu Smith-Schuster anchor the pass game with Noah Gray and Robert Tonyan adding depth. The Chiefs’ o-line must hold up to let Mahomes deploy the air attack and keep the running game functional against a Chargers front led by Mack and Karlaftis. A healthy Brown could unlock a high-ceiling fantasy day if mid-field space opens via deep shots.

Defensively, KC counters Herbert with a pressure plan centered on Jones and Karlaftis, plus Bolton and Chanel in run fits. Travel and Brazil-time wrinkles loom, but the game scripts suggest a likely shootout where Chiefs skill-position players offer robust fantasy days if the protection holds and the field is stretched, even with Rice sidelined early.

Omarion Hampton could emerge as a premier rookie back for the Chargers, with plenty of momentum toward a 1,000-yard ground season and eight rushing scores if the offense carves out a bigger role for him early. The backfield split with Naji Harris will shape his touches, but his burst and vision suggest a workload that could wear defenses down as the season advances.

Keenan Allen anchors a revamped, versatile receiving corps that also features Lad McConkey as a breakout weapon and Quentin Johnston in a role that could grow rapidly. Justin Herbert’s health unlocks more dynamic rushing and explosive plays, while Derwin James and Tulie Tuipulotu hold down a disruptive defensive floor, pushing fantasy upside across the Chargers’ major skill-position pieces.